What is 5-MeO-DMT?
5 meo DMT Retreat. 5-MeO-DMT, sometimes referred to as “The God Molecule”, is a psychedelic in the tryptamine class. It’s found naturally in a wide variety of plant species, and at least one toad species – the Sonoran Desert toad (for more information on this topic, we highly recommend Hamilton Morris’s pamphlet “Bufo Alvarius: The Psychedelic Toad of the Sonoran Desert”).
Meanwhile It is closely related to DMT and 5-HO-DMT, and has traditionally been used as an entheogen in South America during tribal ceremonies.
5-MeO-DMT has sharply risen in popularity over the past few years as many anecdotal reports of its potential as a healing agent have come to light.
Effects
5-Meo-DMT’s psychedelic effects are thought to primarily come from its efficacy as a partial agonist at the 5-HT2A receptor. In particular, it shows a high binding affinity for the 5-HT2A and 5-HT1A subtypes. However, not much is known about these interactions so our understanding of how they result in the psychedelic experience is limited at the current time. Meanwhile
5-MeO-DMT is also thought to inhibit reuptake of the neurotransmitter’s serotonin, noradrenaline, and dopamine, but little is known about the role these mechanisms play. As such, it is strongly advised to avoid combinations with SSRIs, SRIs, MAOIs, RIMAs or any other substance that acts a releasing agent or reuptake inhibitor of monoamine neurotransmitters (serotonin and dopamine for example).
Some of the most commonly reported effects are:
- Stimulation
- Dissociation
- Suppression and release of anxiety
- Feelings of physical and cognitive euphoria
- A sense of unity and interconnectedness
- Catharsis
- Emotion enhancement
- Ego death
- Mindfulness
- Rejuvenation
- Autonomous voice communication
- Thought connectivity
- Time distortion
- Unity and interconnectedness
5 meo DMT Retreat
Potential Side Effects Of 5 meo DMT
- Dizziness
- Respiratory depression
- Increased heart rate
- Muscle contractions
- Muscle spasms
- Muscle tremors
- Motor control loss
- Nausea
- Pupil dilation
- Spatial disorientation
Important: While 5-MeO-DMT and DMT are similar chemically, they have distinct effects and safety profiles from one another, therefore do not substitute 5-MeO-DMT for DMT. They should be regarded as entirely different chemicals and treated as such.
5 meo DMT Retreat
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